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online software optimized crispr design mit  (Addgene inc)


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    Structured Review

    Addgene inc online software optimized crispr design mit
    Online Software Optimized Crispr Design Mit, supplied by Addgene inc, used in various techniques. Bioz Stars score: 95/100, based on 84 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/online+software+optimized+crispr+design+mit/pLKO5%2EsgRNA%2EEFS%2EtRFP+(Plasmid+%2357823)/pmc11449502-347-9-22
    Average 95 stars, based on 84 article reviews
    online software optimized crispr design mit - by Bioz Stars, 2026-09
    95/100 stars

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    Related Articles

    Sequencing:

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
    Article Snippet: .. The sgRNA sequence selection and design was performed using online software Optimized CRISPR Design - MIT ( http://crispr.mit.edu ). pLKO5.sgRNA.EFS.tRFP and pL-CRISPR.SFFV.PAC (Addgene: #57823, #57829) were used as backbone vectors for constitutional sgRNA and Cas9 expression. ..

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK.
    Article Snippet: BRCA1-associated protein 1 (BAP1) has emerged as a major tumor suppressor gene in diverse cancer types, notably in malignant pleural mesothelioma (DPM), and has also been identified as a germline cancer predisposition gene for DPM and other select cancers.. However, its role in the response to DNA damage has remained unclear.. Here, we show that BAP1 inactivation is associated with increased DNA damage both in Met-5A human mesothelial cells and human DPM cell lines.

    Selection:

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
    Article Snippet: .. The sgRNA sequence selection and design was performed using online software Optimized CRISPR Design - MIT ( http://crispr.mit.edu ). pLKO5.sgRNA.EFS.tRFP and pL-CRISPR.SFFV.PAC (Addgene: #57823, #57829) were used as backbone vectors for constitutional sgRNA and Cas9 expression. ..

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK.
    Article Snippet: BRCA1-associated protein 1 (BAP1) has emerged as a major tumor suppressor gene in diverse cancer types, notably in malignant pleural mesothelioma (DPM), and has also been identified as a germline cancer predisposition gene for DPM and other select cancers.. However, its role in the response to DNA damage has remained unclear.. Here, we show that BAP1 inactivation is associated with increased DNA damage both in Met-5A human mesothelial cells and human DPM cell lines.

    Software:

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
    Article Snippet: .. The sgRNA sequence selection and design was performed using online software Optimized CRISPR Design - MIT ( http://crispr.mit.edu ). pLKO5.sgRNA.EFS.tRFP and pL-CRISPR.SFFV.PAC (Addgene: #57823, #57829) were used as backbone vectors for constitutional sgRNA and Cas9 expression. ..

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK.
    Article Snippet: BRCA1-associated protein 1 (BAP1) has emerged as a major tumor suppressor gene in diverse cancer types, notably in malignant pleural mesothelioma (DPM), and has also been identified as a germline cancer predisposition gene for DPM and other select cancers.. However, its role in the response to DNA damage has remained unclear.. Here, we show that BAP1 inactivation is associated with increased DNA damage both in Met-5A human mesothelial cells and human DPM cell lines.

    CRISPR:

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
    Article Snippet: .. The sgRNA sequence selection and design was performed using online software Optimized CRISPR Design - MIT ( http://crispr.mit.edu ). pLKO5.sgRNA.EFS.tRFP and pL-CRISPR.SFFV.PAC (Addgene: #57823, #57829) were used as backbone vectors for constitutional sgRNA and Cas9 expression. ..

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK.
    Article Snippet: BRCA1-associated protein 1 (BAP1) has emerged as a major tumor suppressor gene in diverse cancer types, notably in malignant pleural mesothelioma (DPM), and has also been identified as a germline cancer predisposition gene for DPM and other select cancers.. However, its role in the response to DNA damage has remained unclear.. Here, we show that BAP1 inactivation is associated with increased DNA damage both in Met-5A human mesothelial cells and human DPM cell lines.

    Expressing:

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
    Article Snippet: .. The sgRNA sequence selection and design was performed using online software Optimized CRISPR Design - MIT ( http://crispr.mit.edu ). pLKO5.sgRNA.EFS.tRFP and pL-CRISPR.SFFV.PAC (Addgene: #57823, #57829) were used as backbone vectors for constitutional sgRNA and Cas9 expression. ..

    Article Title: The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK.
    Article Snippet: BRCA1-associated protein 1 (BAP1) has emerged as a major tumor suppressor gene in diverse cancer types, notably in malignant pleural mesothelioma (DPM), and has also been identified as a germline cancer predisposition gene for DPM and other select cancers.. However, its role in the response to DNA damage has remained unclear.. Here, we show that BAP1 inactivation is associated with increased DNA damage both in Met-5A human mesothelial cells and human DPM cell lines.



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    95
    Addgene inc online software optimized crispr design mit
    Online Software Optimized Crispr Design Mit, supplied by Addgene inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/online+software+optimized+crispr+design+mit/pLKO5%2EsgRNA%2EEFS%2EtRFP+(Plasmid+%2357823)/pmc11449502-347-9-22
    Average 95 stars, based on 1 article reviews
    online software optimized crispr design mit - by Bioz Stars, 2026-09
    95/100 stars
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